Friday, 14 December 2012

How to Lower Creatinine and Urea Nitrogen


The level of serum creatinine and urea nitrogen can to a certain degree reflect the severity of damages of the glomerular filtration function. Persistent increase of creatinine and urea nitrogen is an indicator of renal damages.
Serum creatinine is the metabolic waste of muscle and every 20g muscle can produce 1mg creatinine. Creatinine is mainly discharged out of the body through the filtration ability of the glomeruli.
Urea nitrogen is the end product of protein metabolism and every 1g protein can produce 0.3g urea which contains nearly half urea nitrogen. Kidney is the main organ to excrete urea nitrogen. When urea nitrogen is filtered out of the glomeruli, it can be re-absorbed in the renal tubules. The more rapidly the urine passes through the tubules, the less urea nitrogen will be re-absorbed. Besides renal damages, there are other factors that can raise urea nitrogen level including high-protein diet, gastrointestinal bleeding, dehydration and high catabolism.
In the early stage of renal impairments, the serum creatinine and urea nitrogen can in normal range and when the glomerular filtration rate (GFR) is reduced more than 50% can there be obvious increase of creatinine and urea nitrogen and patients will have a series of symptoms and discomforts such as diuresis, increase night urine, thirsty, mucous membrane drying, fatigue, edema, hypertension, pulmonary edema, heart failure, etc.
Immune clearance is to adopt blood purification equipments to clear the metabolic wastes and toxins out of the body. Immune clearance is more thorough than dialysis which can only discharge small molecular toxins like creatinine, urea nitrogen and uric acid. Immune clearance include not only dialysis but also blood filtration, blood perfusion, immune adsorption, etc which can not only discharge wastes of small molecular but also wastes of large molecular as well as immune complexes.
Immune clearance is one step of immunotherapy which aims at repairing renal damages and regulating immune disorders. The root cause of creatinine and urea nitrogen increase is glomerular sclerosis, injury of the micro-circulation and basement membrane. So long as these damages are repaired can the creatinine and urea nitrogen be reduced naturally.
So lower  Creatinine  make your body comfortable and keep your kidney function ,dialysis is a common way to lower creatinine ,but  it have many side effect such as nausea ,vomit, high fever and so on . Immune Clearance can effect reduce creatinine and avoid these side effect .

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