Anemia In Renal Failure

In patients with chronic kidney disease, normochromic normocytic anaemia mainly develops from decreased renal synthesis of erythropoietin. The anaemia becomes more severe as the GFR (glomerular filtration rate) progressively decreases. No reticulocyte response occurs, red blood cell survival is decreased, and there is an associated increased bleeding tendency due to uraemia-induced platelet dysfunction.
1. Renal failure affect hematopoiesis
Renal failure, in addition to the damaged kidneys produce erythropoietin, hemoglobin, the oxygen affinity of lower units hemoglobin increase the utilization of oxygen is relatively serious, kidney ischemia, resulting in the reduction of the main stimulus for erythropoietin, leading to erythrocyte generation of EPO significantly reduced. There are toxins inhibit bone marrow, renal failure when the accumulation of certain toxic substances in the blood has a direct inhibitory effect on bone marrow, leading to hematopoietic dysfunction, and thus give rise to anemia.
2. Kidney failure cause red blood cell destruction:
Some patients with chronic renal failure increased red blood cell destruction is also one of the reasons leading to renal failure anemia, which is due to the high polyamine hyperlipidemia in uremia lead to shortened red blood cell life occurred autolysis uremic the RBC metabolic disorders and increased erythrocyte fragility The microangiopathy red blood cells by mechanical damage and destruction caused by red blood cell autolysis Hypersplenism. The patients had better watch out.
3.  renal failure, the reason will lead to the emergence of anemia, mostly due to insufficient blood volume, hypoperfusion caused. This is the case should go to the formal medical treatment.
Renal failure patients with anemia most patients will appear, so patients with mental Do not panic, maintain calm and collected. With the medical treatment, kidney failure, recovery of normal renal function, renal anemia will come good.

Symptoms of kidney failure in women

With society developing, more and more women tend to work outside. Those women are respectable because they not only strive for benefits during working but also are occupied in housework. For most women, looking after children and parents, cooking, doing house work are their responsibilities as mothers and daughters. However, they usually ignore their own health. According to the reports of outpatient service in our hospital, many women are diagnosed as the late stages of Kidney Failure on their first checkup. The reason for this problem is that they have no ideal about the early stages of kidney Failure.
Causes of kidney failure include:
Diabetes
High blood pressure.
Glomerular diseases (attacks the tiny blood vessels, or glomeruli, within the kidney).
Genetic kidney diseases.
Poisons and trauma, such as a direct and forceful blow to the kidneys.
Some dietary supplements and over-the-counter medicines can be poisonous to the kidneys if taken regularly over a period of time.
When symptoms of kidney failure do appear, they may include:
Swelling, especially of the legs and feet.
Little or no urine output.
Thirst and a dry mouth.
Rapid heart rate.
Feeling dizzy when you stand up.
Loss of appetite, nausea, and vomiting.
Feeling confused, anxious and restless, or sleepy.
Pain on one side of the back, just below the rib cage and above the waist (flank pain).